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Restoration of p53 tumor-suppressor activity in human tumor cells in vitro and in their xenografts in vivo by recombinant avian adenovirus CELO-p53

✍ Scribed by Logunov, D Y; Ilyinskaya, G V; Cherenova, L V; Verhovskaya, L V; Shmarov, M M; Chumakov, P M; Kopnin, B P; Naroditsky, B S

Book ID
110039441
Publisher
Nature Publishing Group
Year
2003
Tongue
English
Weight
255 KB
Volume
11
Category
Article
ISSN
0969-7128

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## Abstract Berberine has been shown to have anti‐carcinogenic effects. Since p53 is the most commonly mutated tumor suppressor gene, and a lack of functional p53 is associated with an increased risk of cancer development, we examined the effects of berberine on p53‐positive and p53‐deficient non‐s