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Restoration of expression of signal-transduction molecules in lymphocytes from patients with metastatic renal cell cancer after combination immunotherapy

✍ Scribed by Jan W. Gratama; Arnold H. Zea; Reinder L. H. Bolhuis; Augusto C. Ochoa

Publisher
Springer-Verlag
Year
1999
Tongue
English
Weight
117 KB
Volume
48
Category
Article
ISSN
0340-7004

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We and others have shown decreased expression of T-cell receptor-CD3-associated signal transducing molecules (TCR) in tumor infiltrating and peripheral T cells of patients with advanced cancer. In the present study, we performed adoptive immunotherapy (AIT) with tumor-associated lymphocytes (TAL) in