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Restoration of Clostridium Difficile Toxin-B-Inhibited Phospholipase D by Phosphatidylinositol 4,5-Bisphosphate

✍ Scribed by Martina Schmidt; Ulrich Rümenapp; Christoph Nehls; Sabine Ott; Jutta Keller; Christoph Von Eichel-Streiber; Karl H. Jakobs


Book ID
115132219
Publisher
John Wiley and Sons
Year
1996
Tongue
English
Weight
664 KB
Volume
240
Category
Article
ISSN
1432-1327

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Activation of cellular phospholipase A2
✍ Maria Caspar Shoshan; Inger Florin; Monica Thelestam 📂 Article 📅 1993 🏛 John Wiley and Sons 🌐 English ⚖ 860 KB

C difficile toxin B i s a potent cytotoxin known to disrupt the microfilaments of cultured cells We have recently shown also increased phospholipase A2 activity in cells treated with toxin B The activity was detected as a toxin-induced, dose-dependent release of 14C-arachidonic acid from prelabeled