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Restless legs syndrome in Parkinson's disease: A case-controlled study

✍ Scribed by Pudukode R. Krishnan; Manvir Bhatia; Madhuri Behari

Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
57 KB
Volume
18
Category
Article
ISSN
0885-3185

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✦ Synopsis

Abstract

Restless legs syndrome (RLS) is a disorder of motor activity with a circadian pattern, occurring frequently in patients with Parkinson's disease (PD). We sought to estimate the prevalence of RLS in Indian PD patients. One hundred twenty‐six consecutive PD patients and 128 healthy age‐ and sex‐matched controls were evaluated using a predesigned questionnaire. RLS was present in 10 of 126 cases of PD (7.9%) and 1 of 128 controls (0.8%, P = 0.01). PD patients with RLS were older than those without RLS (63.70 ± 7.80 years vs. 57.37 ± 10.04 years; P = 0.05) and had higher prevalence of depression (40% vs. 10.3%; P = 0.023). No demographic factors or factors related to PD correlated with the presence or severity of RLS. RLS is more common among patients with PD than controls. A greater medical recognition of this disorder is needed in view of available effective treatment. © 2002 Movement Disorder Society

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