𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Restless legs syndrome in a population of northern Tanzania: A community-based study

✍ Scribed by Andrea Sylvia Winkler; Anna Trendafilova; Michael Meindl; John Kaaya; Erich Schmutzhard; Jan Kassubek

Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
102 KB
Volume
25
Category
Article
ISSN
0885-3185

No coin nor oath required. For personal study only.

✦ Synopsis

Abstract

Restless legs syndrome (RLS) is a highly prevalent movement disorder. However, prevalences seem to vary amongst different ethnicities. To date, no community‐based prevalence studies on RLS have been reported from the African continent. We have conducted a community‐based, door‐to‐door study in northern Tanzania. Over a period of 16 months, 7,654 people aged 14 years and older were screened for the RLS Essential Diagnostic Criteria. Sampling was performed according to the method of “multistage cluster sampling.” People who screened positive where reinterviewed and physically examined by a specialist neurologist. During the screening phase, 10 people answered “yes” to at least one of the screening questions. After reinterviewing those people, the result was confirmed in five people only. After careful re‐evaluation of the results, only one person was diagnosed with RLS. Because of methodological limitations a definite prevalence may only be calculated from larger population‐based studies of different African ethnicities with screening questions adapted to the cultural context. © 2010 Movement Disorder Society

📜 SIMILAR VOLUMES

Prevalence of restless legs syndrome in
Prevalence of restless legs syndrome in a rural community in Japan
✍ Takashi Nomura; Yuichi Inoue; Masayoshi Kusumi; Yusuke Uemura; Kenji Nakashima 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 155 KB 👁 1 views

## Abstract To assess the prevalence and clinical significance of restless legs syndrome (RLS) in a Japanese population, we carried out a community‐based survey in a rural area of Japan. We sent questionnaires requesting information on demographics, the Center for Epidemiological Studies Depression

Restless legs syndrome: Epidemiological
Restless legs syndrome: Epidemiological and clinicogenetic study in a South Tyrolean population isolate
✍ Florian D. Vogl; Irene Pichler; Susanna Adel; Gerd K. Pinggera; Stefano Bracco; 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 168 KB 👁 1 views

Genetic contributions to restless legs syndrome (RLS) have been consistently recognized from population and family studies. To determine the clinical and genetic features of RLS in a population isolate and explore linkage to three previously described susceptibility loci on chromosomes 12q, 14q, and

Restless legs syndrome in Friedreich ata
Restless legs syndrome in Friedreich ataxia: A polysomnographic study
✍ Birgit Frauscher; Sascha Hering; Birgit Högl; Viola Gschliesser; Hanno Ulmer; We 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 118 KB

Friedreich ataxia (FA) is the most common type of hereditary ataxia. Frataxin deficiency due to a GAA expansion in the first intron of chromosome 9 results in intramitochondrial iron accumulation. On the basis of the patients' complaints about sleep disturbance and pathophysiological considerations,

Family-based association study of the re
Family-based association study of the restless legs syndrome loci 2 and 3 in a European population
✍ David Kemlink; Olli Polo; Pasquale Montagna; Federica Provini; Karin Stiasny-Kol 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 90 KB 👁 1 views

## Abstract Three loci for the restless legs syndrome (RLS) on chromosomes 12q, 14q, and 9p (RLS1, RLS2, and RLS3) have been mapped, but no gene has been identified as yet. RLS1 has been confirmed in families from three different populations. We conducted a family‐based association study of 159 Eur

Restless legs syndrome in multiple scler
Restless legs syndrome in multiple sclerosis: A case-control study
✍ Marcello Deriu; Giovanni Cossu; Andrea Molari; Daniela Murgia; Alessandra Mereu; 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 81 KB 👁 1 views

## Abstract The aim of our study was to explore restless legs syndrome (RLS) frequency in multiple sclerosis (MS)‐patients and establish whether RLS could be a symptom of MS. Over a period of 1 year, we consecutively enrolled 202 MS‐patients and 212 healthy controls, matched for sex and age, in a c

Family-based and population-based associ
Family-based and population-based association studies validate PTPRD as a risk factor for restless legs syndrome
✍ Qinbo Yang; Lin Li; Rong Yang; Gong-Qing Shen; Qiuyun Chen; Nancy Foldvary-Schae 📂 Article 📅 2011 🏛 John Wiley and Sons 🌐 English ⚖ 103 KB 👁 1 views

## Abstract ## Objective: We previously mapped a genetic locus for restless legs syndrome (RLS) to chromosome 9p22‐24 (__RLS3__) and a later genome‐wide association study (GWAS) implicated the __PTPRD__ gene at the __RLS3 l__ocus as a susceptibility gene for RLS. However, from the standpoint of ge