## Abstract Substantia nigra (SN) hypoechogenicity assessed by transcranial B‐mode sonography (TCS) is typical for idiopathic restless legs syndrome (RLS). Here, we investigated whether SN hypoechogenicity may differentiate between polyneuropathy (PNP) patients with and without RLS. Seventy‐five pa
Restless Legs and Substantia Nigra Hypoechogenicity are Common Features in Friedreich’s Ataxia
✍ Scribed by Matthis Synofzik; Jana Godau; Tobias Lindig; Ludger Schöls; Daniela Berg
- Book ID
- 107648368
- Publisher
- Springer-Verlag
- Year
- 2010
- Tongue
- English
- Weight
- 138 KB
- Volume
- 10
- Category
- Article
- ISSN
- 1473-4222
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract Pathological studies demonstrate a decreased iron content in the substantia nigra (SN) contributing to the pathophysiology of restless legs syndrome (RLS). SN echogenicity as measured by transcranial sonography (TCS) correlates with the SN iron content. The objective of this study was t
## Abstract The cause of restless legs syndrome (RLS) is unknown, but an involvement of the dopaminergic system and a possible relation to Parkinson's disease (PD) is suggested by the positive response to dopaminergic treatment. We imaged the striatal dopamine transporter with [^123^I] __N__‐(3‐iod