Resting energy expenditure should be measured in patients with cirrhosis, not predicted
✍ Scribed by Angela M. Madden; Dr. Marsha Y. Morgan
- Publisher
- John Wiley and Sons
- Year
- 1999
- Tongue
- English
- Weight
- 226 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0270-9139
No coin nor oath required. For personal study only.
✦ Synopsis
Measurements of resting energy expenditure (REE) can be used to determine energy requirements. Prediction formulae can be used to estimate REE but have not been validated in cirrhotic patients. REE was measured, by indirect calorimetry, in 100 cirrhotic patients and 41 comparable healthy volunteers, and the results compared with estimates predicted using the Harris-Benedict, Schofield, Mifflin, Cunningham, and Owen formulae, and the disease-specific Mu ¨ller formula. The mean (؎ 1 SD) measured REE in the healthy volunteers (1,590 ؎ 306 kcal/24 h) was significantly greater than the mean Harris-Benedict, Mifflin, Cunningham, and Owen predictions but comparable with the mean Schofield prediction; individual predicted values varied widely from measured values (95% limits of agreement, ؊460 to ؉424 kcal). The mean measured REE in the cirrhotic patients was significantly greater than in the healthy volunteers (23.2 ؎ 3.8 cf 21.9 ؎ 2.9 kcal/kg/24 h; P F .05). The mean measured REE in the cirrhotic patients (1,660 ؎ 337 kcal/24 h) was significantly different from mean predicted values (Harris-Benedict,