Attempts have been made to develop sublines of MCF-7 cells resistant to the growth-inhibitory actions of medroxyprogesterone acetate (MPA), dexamethazone (DEX), antioestrogens or high-dose oestradiol (Ed by prolonged exposure to high hormone concentrations. While high degrees of resistance to MPA, D
β¦ LIBER β¦
Responsiveness to Hormone, Growth Factor and Drug Treatment of a Human Breast Cancer Cell Line: Comparison between Early and Late Cultures
β Scribed by Alessandra de Cupis, Paolo Pirani, Laura Fazzuoli and Roberto E. Favoni
- Book ID
- 125624677
- Publisher
- Society for In Vitro Biology
- Year
- 1998
- Tongue
- English
- Weight
- 818 KB
- Volume
- 34
- Category
- Article
- ISSN
- 1475-2689
- DOI
- 10.2307/4294875
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## Abstract Prolonged hypoxia induced transient drug resistance in Chinese hamster lung fibroblasts. Previously hypoxic cells were resistant to adriamycin and resistant to etoposide. Complete recovery of etoposide sensitivity was observed following reβaeration for 24 hr. A change in Pβglycoprotein