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RESPONSIVENESS OF HYPERTENSIVE SUBJECTS TO PRAZOSIN

✍ Scribed by G. S. Stokes; J. C. Monaghan; E. P. MacCarthy; H. F. Oates

Book ID
108932908
Publisher
John Wiley and Sons
Year
1980
Tongue
English
Weight
164 KB
Volume
7
Category
Article
ISSN
0305-1870

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Ketanserin, a serotonin antagonist, is effective in lowering portal pressure in a rat model of portal hypertension. As ketanserin has al-adrenoceptor-blocking properties in addition to its serotonin-blocking effects, we sought to define further the mechanism of ketanserin's portal pressure-lowering