Responses to antipsychotic therapy among patients with schizophrenia or schizoaffective disorder and either predominant or prominent negative symptoms

Dopamine receptor D3 genotype associatio

Dopamine receptor D3 genotype association with greater acute positive symptom remission with olanzapine therapy in predominately caucasian patients with chronic schizophrenia or schizoaffective disorder

✍ David H. Adams; Sandra Close; Mark Farmen; AnnCatherine M. Downing; Alan Breier; 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 154 KB

## Abstract ## Objective To test association of dopamine receptor D3 (DRD‐3) gene polymorphisms with olanzapine response in genetic samples from a registration phase clinical trial. ## Methods Eighty‐eight acutely ill patients with schizophrenia or schizoaffective disorder were genotyped for ser