Response to therapy is independently associated with survival prolongation in chronic myelogenous leukemia in the blastic phase
โ Scribed by Hagop M. Kantarjian; Jianqin Shan; Terry Smith; Moshe Talpaz; Peter Kozuch; Mary Beth Rios; Jorge Cortes; Francis J. Giles; Susan O'Brien
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 106 KB
- Volume
- 92
- Category
- Article
- ISSN
- 0008-543X
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## BACKGROUND. T-cell lymphoid blastic phase (BP) transformation is rare in chronic myelogenous leukemia (CML). 2-amino-9-โค-D-arabinosyl-6-methoxy-9H-guanine (GW506U78), a prodrug of arabinosylguanine (ara-G), is effective in T-cell leukemias. ## METHODS. The authors present a case of a 48-year