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Response to the comments on the commentary ‘prediction of absolute bioavailability for drugs using oral and renal clearance following a single oral dose: a critical view’

✍ Scribed by Iftekhar Mahmood

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 84 KB
Volume: 19
Category: Article
ISSN: 0142-2782
DOI: 10.1002/(sici)1099-081x(199810)19:7<483::aid-bdd140>3.0.co;2-y

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PREDICTION OF ABSOLUTE BIOAVAILABILITY F

PREDICTION OF ABSOLUTE BIOAVAILABILITY FOR DRUGS USING ORAL AND RENAL CLEARANCE FOLLOWING A SINGLE ORAL DOSE: A CRITICAL VIEW

✍ IFTEKHAR MAHMOOD 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 115 KB 👁 1 views

In order to determine the absolute bioavailability, both oral and intravenous administrations of a drug are often used. Recently a new method has been proposed to determine absolute bioavailability in the absence of intravenous dose. Following a single oral dose, this method requires oral and renal

Commentary ’Prediction of absolute bioav

Commentary ’Prediction of absolute bioavailability for drugs using oral and renal clearance following a single oral dose: A critical review ‘ (I. Mahmood)

✍ Peter H. Hinderling 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 70 KB 👁 1 views

We wish to comment on the paper by Mahmood, `Prediction of absolute bioavailability for drugs using oral and renal clearance following a single oral dose: a critical review'. 1 We ®rst present below a summary of the main features of the novel method, its validation, and the prerequisites for its suc