Response to second-line chemotherapy in patients with hormone refractory prostate cancer receiving two sequences of mitoxantrone and taxanes
β Scribed by William K. Oh; Judith Manola; Vladana Babcic; Neesha Harnam; Philip W. Kantoff
- Book ID
- 116945724
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 129 KB
- Volume
- 67
- Category
- Article
- ISSN
- 0090-4295
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## Abstract ## BACKGROUND. This randomized, noncomparative, multicenter, clinical trial evaluated ixabepilone or mitoxantrone/prednisone (MP) as secondβline chemotherapy for taxaneβrefractory, hormoneβrefractory, prostate cancer (HRPC). ## METHODS. Patients with HRPC that progressed during or wi
in tumor samples was determined by immunohistochemical staining and Western blot analysis. GSH concentration was measured by an enzymatic assay. Department of Obstetrics and Gynecology, Tot- ## RESULTS. The response rate was 38.4%. The estimated 3-year survival rate for tori University School of
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