## Abstract The safety and efficacy of pegylated interferon (PEG‐IFN) alfa‐2a and ribavirin were studied among patients treated for genotype 4 chronic hepatitis C. Ninety‐five patients with chronic hepatitis C genotype 4 were treated with PEG‐IFN alfa‐2a (180 µg/week) plus ribavirin (≥11 mg/kg/day)
Response to pegylated interferon plus ribavirin in HIV-infected patients with chronic hepatitis C due to genotype 4
✍ Scribed by L. Martín-Carbonero; M. Puoti; J. García-Samaniego; A. De Luca; E. Losada; G. Quinzan; R. Bruno; A. Mariño; M. González; M. Núñez; V. Soriano
- Book ID
- 108886170
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 132 KB
- Volume
- 15
- Category
- Article
- ISSN
- 1352-0504
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Single nucleotide polymorphisms (SNPs) near the interleukin 28B (IL28B) region are the strongest baseline predictors of a sustained virologic response (SVR) to peg-interferon (PegIFN) and ribavirin (Rbv) in patients with hepatitis C virus (HCV) genotype 1 infection. Whether this holds true for HCV-4
In patients chronically infected with hepatitis C virus (HCV) genotype 4, the optimum duration of therapy and the predictors of sustained virologic response (SVR) have not been adequately determined. In this study, 358 patients with chronic hepatitis C genotype 4 were randomly assigned to pegylated