✦ LIBER ✦
Response to gallamine: An indicator of diminished neuromuscular function in experimental autoimmune myasthenia gravis
✍ Scribed by C. L. Hinman; G. E. Dambach; R. A. Hudson; H. C. Rauch
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 486 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0360-4012
No coin nor oath required. For personal study only.
✦ Synopsis
A test for diminished neuromuscular function in animals with experimental autoimmune myasthenia gravis is described. Within minutes following an injection of gallamine triethiodide, mice exhibit a dramatic yet transient response which is dose-dependent. Mice previously inoculated with acetylcholine receptor are approximately twice as sensitive to gallamine as normal mice. Positive results have been found in over 80% of receptor-inoculated BALB/c mice and in 94% of C57Bl/6 mice.