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Response of the adult newt ventricle to injury

✍ Scribed by Oberpriller, John O. ;Oberpriller, Jean C.

Publisher
John Wiley and Sons
Year
1974
Tongue
English
Weight
923 KB
Volume
187
Category
Article
ISSN
0022-104X

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✦ Synopsis

Abstract

A study was made of the response of adult newt ventricle to injury. The major events in the repair process after wounding involve blood clot formation, coagulation necrosis, macrophagic activity, regenerative activity of heart muscle, and connective tissue formation. Light microscopic autoradiography indicated that there was a definite area of labeled cells in trabeculae adjacent to the wound, beginning at about ten days after injury. Electron microscopic autoradiography confirmed that myocytes containing myofibrillae underwent DNA synthesis. It was concluded that adult newt myocardium is capable of reacting to injury by the proliferation of myocytes at the wound area as indicated by both DNA synthesis and mitosis.

πŸ“œ SIMILAR VOLUMES

Responses of denervated adult newt limb
Responses of denervated adult newt limb stumps to reinnervation and reinjury
✍ Salley, Judith D. ;Tassava, Roy A. πŸ“‚ Article πŸ“… 1981 πŸ› John Wiley and Sons 🌐 English βš– 738 KB

## Abstract It is well known that denervated adult newt limbs do not regenerate. Not understood is why denervated newt limb stumps fail to initiate regeneration upon reinnervation. In an effort to define the regeneration limiting factors, we examined the histology of long‐term denervated newt limb