In order to explore further the role of laser for microneural repair, the effect of CO 2 laser irradiation on intact rat sciatic nerves was investigated. In total 40 rat sciatic nerves were exposed to 12 different combinations of laser power (50, 100, and 150 mW) and pulse duration (0.1 to 3 s) norm
Response of peripheral nerve to He-Ne laser: Experimental studies
โ Scribed by Dr. S. Rochkind; M. Nissan; L. Barr-Nea; N. Razon; M. Schwartz; A. Bartal
- Publisher
- John Wiley and Sons
- Year
- 1987
- Tongue
- English
- Weight
- 290 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0196-8092
No coin nor oath required. For personal study only.
โฆ Synopsis
Low-energy He-Ne laser irradiation (LELI) was found to affect the electric activity and morphology in both intact and severely injured peripheral nerves in rats. Action potential (AP) in the healthy nerve increased by 33% following a single transcutaneous irradiation. Similar irradiation in crushed nerves caused AP to increase significantly over the AP of nonirradiated crushed nerve. Morphological observations revealed that a laser-irradiated injured nerve had diminished scar tissue as compared to an injured but not an irradiated nerve.
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## Abstract Age is the most important predictor of clinical outcome after peripheral nerve injury. The stability of the neuromuscular junction (NMJ) after denervation is thought to be central to neuromuscular recovery. Stability is characterized by maintenance of the motor endplate and mRNA upregul