A male patient with advanced breast cancer had no response to orchiectomy but subsequently enjoyed a 17-month partial response to tamoxifen 10 mg B.I.D. His tumor estrogen receptor (ER) protein was 555 fmol proteinhl cytosol. The potential role of ER determinations in the selection of therapy for ad
โฆ LIBER โฆ
Response of metastatic breast cancer to tamoxifen withdrawal: Report of a case
โ Scribed by Dr. William Stein III; Gabriel N. Hortobagyi; George R. Blumenschein
- Publisher
- John Wiley and Sons
- Year
- 1983
- Tongue
- English
- Weight
- 514 KB
- Volume
- 22
- Category
- Article
- ISSN
- 0022-4790
No coin nor oath required. For personal study only.
โฆ Synopsis
This case history describes a patient with metastatic breast cancer treated sequentially with diethylstilbestrol, drug withdrawal, tamoxifen, and drug withdrawal again. An objective response was observed in all four instances. Withdrawal responses to tamoxifen exist and should be kept in mind for selected patients.
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