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Response of human HT-29 colorectal tumor cells to extended exposure to bromodeoxyuridine

✍ Scribed by Jonathan Maybaun; Mikehl S. Hafner; Eric C. Burton; Philip L. Stetson; William D. Ensminger; Clare E. Rogers

Book ID
104890935
Publisher
Springer
Year
1989
Tongue
English
Weight
704 KB
Volume
25
Category
Article
ISSN
0344-5704

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## Abstract Flavone and camptothecin were both shown to potently induce apoptosis in HT‐29 human colon cancer cells. Whereas camptothecin acts on the basis of topoisomerase‐I inhibition, flavone appears to burst mitochondrial production of reactive oxygen species by increasing respiratory chain act