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Response: Characteristics of IL-17-Producing γδ T Cells

✍ Scribed by Caroline E. Sutton; Stephen J. Lalor; Cheryl M. Sweeney; Corinna F. Brereton; Ed C. Lavelle; Kingston H.G. Mills


Book ID
108152539
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
58 KB
Volume
32
Category
Article
ISSN
1074-7613

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## Abstract Based on the evidence that IL‐17 is a key cytokine involved in various inflammatory diseases, we explored the critical role of IL‐17‐producing γδ T cells for tumor development in tumor‐bearing mouse model. IL‐17^−/−^ mice exhibited a significant reduction of tumor growth, concomitantly