Respiratory responses of humans exposed to an aerosol–gas pollutant mixture: Multivariate contrast of a complex atmosphere to clean air and sodium chloride aerosol controls
✍ Scribed by M. T. Kleinman; R. M. Bailey; W. S. Linn; J. D. Whynot; K. R. Anderson; T. G. Venet; J. D. Hackney
- Publisher
- John Wiley and Sons
- Year
- 1984
- Tongue
- English
- Weight
- 621 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0260-437X
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✦ Synopsis
Data from a group of 20 subjects with normal baseline pulmonary function, who were exposed for 2 h to a test atmosphere containing a complex mixture of pollutants, have been contrasted with data from two other groups exposed to presumably non-toxic control atmospheres. Group 1 was exposed to clean air, group 2 was exposed to clean air containing sodium chloride aerosol at 270 pg m-3, and group 3 was exposed to the complex atmosphere containing sodium chloride (332 pg m-3) and zinc ammonium sulfate (23 pg m-3) aerosols plus nitrogen dioxide (0.5 ppm) and sulfur dioxide (0.5 ppm). These atmospheres (ranked according to the presumed relative toxicities of the components; clean air = 0, sodium chloride = 1, complex mixture = 2) were contrasted using multiple regression and partial correlation analyses. The effects of exposure to the complex gas-aerosol mixture on forced expiratory performance were not significantly different from those observed in subjects exposed to clean air or to sodium chloride aerosol.