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Respiratory mechanics: Comparison of beagle dogs, göttingens minipigs and cynomolgus monkeys

✍ Scribed by Simon Authier; Leslie Gold; Annette Robichaud; Julie Gervais; Said Maghezzi; Thomas Schuessler; Eric Toncy

Book ID
113941969
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
55 KB
Volume
62
Category
Article
ISSN
1056-8719

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To determine the usefulness of monkey as an animal model, bioavailability and in vivo release behaviors of theophylline (TP) after oral administration of controlled-release beads in dogs, monkeys, and minipigs were evaluated. Controlled-release beads were prepared using a centrifugal-fluid type gran