Respiratory effects of exposure to low levels of concrete dust containing crystalline silica
β Scribed by E. Meijer; H. Kromhout; D. Heederik
- Publisher
- John Wiley and Sons
- Year
- 2001
- Tongue
- English
- Weight
- 132 KB
- Volume
- 40
- Category
- Article
- ISSN
- 0271-3586
No coin nor oath required. For personal study only.
β¦ Synopsis
Abstract
Background
Dusts containing crystalline silica are generated in mining, construction, glass, granite and concrete production industries. The association between exposure to low levels of concrete dust containing crystalline silica and reduction in lung function, was evaluated in a crossβsectional study.
Methods
The study was carried out among 144 concrete workers, from two factories, with exposure assessment of respirable dust and silica by personal samplers. Results of respiratory questionnaires and standardized measurements of lung function were compared with the results in a control population. Multiple linear regression analysis was used in selecting factors that predict (age and standing height standardized residual) lung function.
Results
The average concentration of respirable dust in both factories was 0.8 mg/m^3^ and 0.06 mg/m^3^ for respirable silica. The average silica content of the dust was 9%. The average cumulative dust exposure was 7.0 mg/m^3^ year and cumulative silica exposure was 0.6 mg/m^3^ year. Significant associations between exposure to concrete dust and a small lung function (FEV~1~/FVC ratio, MMEF) loss were found, independent of smoking habits and of a history of allergy.
Conclusions
Our results indicate that, concrete workers with chronic obstructive pulmonary symptoms and/or workβrelated lower respiratory symptoms are at risk of having a reduction in lung function (FEV&~1~/FVC ratio) outside the 5th percentile of the external reference population, and therefore, of mild chronic obstructive pulmonary disease, at respirable concrete dust levels below 1 mg/m^3^ with a respirable crystalline silica content of 10% (TWA, 8 hr). Am. J. Ind. Med. 40:133β140, 2001. Β© 2001 WileyβLiss, Inc.
π SIMILAR VOLUMES
Exposure to ionizing radiation (IR) was used to alter gonadal growth in brook charr (Salvelinus fontinalis). To evaluate the possible effects of low-level doses of IR on future seawater adaptability of brook charr, the physiological state and growth performances of juvenile brook charr were examined
Human HL-60 cells were exposed for 20 min to an electromagnetic field at frequencies ranging from 15 to 150 Hz and at densities from 0.2 to 2.3 mT (2 to 23 gauss). Following each exposure, quantitative levels of c-myc and histone H2B transcripts were determined by dot-blot hybridization analyses and