Respiratory chain complex I deficiency
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Triepels, R.H. ;Van Den Heuvel, L.P. ;Trijbels, J.M. ;Smeitink, J.A.
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Article
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2001
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John Wiley and Sons
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English
⚖ 151 KB
## Abstract Oxidative phosphorylation disorders make a contribution of 1 per 10,000 live births in man, of which isolated complex I deficiency is frequently the cause. Complex I, or NADH:ubiquinone oxidoreductase, is the largest multi‐protein enzyme complex of the mitochondrial electron transfer ch