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Respiratory allergy and pulmonary irritation to trimellitic anhydride in Brown Norway rats

✍ Scribed by Josje H.E Arts; Nanne Bloksma; Thea Leusink-Muis; C.Frieke Kuper


Book ID
114086978
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
255 KB
Volume
187
Category
Article
ISSN
0041-008X

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## Abstract A rat bioassay has been developed to provide an objective approach for the identification and classification of respiratory allergy using trimellitic anhydride (TMA), which is a known respiratory tract irritant and asthmagen. Particular emphasis was placed on the study of route‐of‐induc