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Resonance Raman spectroscopy as an effective tool for the determination of antioxidative stability of cosmetic formulations

✍ Scribed by Maxim E. Darvin; Wolfram Sterry; Jürgen Lademann


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
124 KB
Volume
3
Category
Article
ISSN
1864-063X

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✦ Synopsis


Abstract

Carotenoids beta‐carotene, lutein, lycopene and others are well‐known powerful antioxidants acting as an effective neutralizer of free radicals produced in the human organism as a result of the influence of stress factors, such as UV irradiation. The protective effect of antioxidants is used in cosmetic products to increase the skin protection against the destructive action of free radicals and for the stabilization of formulations against oxidation. In the skin, the different antioxidant substances form protection chains to avoid their destruction by the interaction with the free radicals. Similar effects have to be expected also in topically applied formulations. In the present study the influence of different mixtures of antioxidants (beta‐carotene, vitamins C and E) on the stability of antioxidants in formulations used for skin treatment was investigated. The measurements were carried out by using non‐invasive resonance Raman spectroscopy for the detection of the carotenoid concentration in the cosmetic formulations. (© 2010 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim)