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Resonance assignment and secondary structure of the cold shock domain of the human YB-1 protein

✍ Scribed by Cathelijne P. A. M. Kloks; Astrid Hoffmann; James G. Omichinski; Geerten W. Vuister; Cornelis W. Hilbers; Stephan Grzesiek

Book ID
110261713
Publisher
Springer Netherlands
Year
1998
Tongue
English
Weight
30 KB
Volume
12
Category
Article
ISSN
0925-2738

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Antibody heavy chain variable domains (VH) lacking their light chain (VL) partner are prime candidates for the design of minimum-size immunoreagents. To obtain structural information about isolated VH domains, a human VH was labelled with 15N or doubly labelled with both 15N and 13C and was studied