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Resolving the enigma of prebiotic COP bond formation: Prebiotic hydrothermal synthesis of important biological phosphate esters

✍ Scribed by Gull Maheen; Ge Tian; Yingwu Wang; Chao He; Zhan Shi; Hongming Yuan; Shouhua Feng


Publisher
John Wiley and Sons
Year
2010
Tongue
English
Weight
246 KB
Volume
21
Category
Article
ISSN
1042-7163

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✦ Synopsis


Abstract

Important biological phosphate esters such as sn‐glycerol‐3‐phosphate, glycerol‐2‐phosphate, and phosphoethanolamine were synthesized under hydrothermal conditions. Phosphorus was incorporated into the biomolecules, leading to the formation of COP type compounds hydrothermally. Only perlite‐catalyzed reaction at 180°C could result in the formation of sn‐glycerol‐3‐phosphate, whereas glycerol‐2‐phosphate could be easily synthesized at 100°C with or without minerals and phosphoethanolamine was obtained within a temperature range of 100 to 120°C. © 2010 Wiley Periodicals, Inc. Heteroatom Chem 21:161–167, 2010; Published online in Wiley InterScience (www.interscience.wiley.com). DOI 10.1002/hc.20591