Resolution of racemic R.S-α-arylethylamine by a new resolving agent (R)thiazolidine-2-thione-4-carboxylic acid
✍ Scribed by Yezhi Li; Chunxiao Guo; Weiming Bu; Huamin Huang
- Book ID
- 105639332
- Publisher
- SP Science China Press
- Year
- 1998
- Tongue
- English
- Weight
- 570 KB
- Volume
- 41
- Category
- Article
- ISSN
- 1674-7291
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📜 SIMILAR VOLUMES
4-Alkyl-2-alkylidene-glutaric acids are easily obtained by a Claisen-Johnson rearrangement, providing a short access to 4-alkyl-ot-ketoglutaric acids. These compounds are substrates of the glutamic oxalacetic transaminase (GOT), allowing the enzymatic synthesis of biologically important analogues of
A New Access to Alkyl-α-ketoglutaric Acids, Precursors of Glutamic Acid Analogues by Enzymatic Transamination. Application to the Synthesis of (2S,4R)-4-Propyl-glutamic Acid. -The new ketoglutarate (V) is easily available by a novel route via Claisen-Johnson rearrangement of ester (I) with orthoest