𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Resolution of biotin intermediate lactone by enzyme-catalyzed stereoselective lactonization in organic solvent

✍ Scribed by Jian-Yong Zheng; Zhao Wang; Qing Zhu; Yin-Jun Zhang; Hong-De Yan

Book ID
113804357
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
317 KB
Volume
56
Category
Article
ISSN
1381-1177

No coin nor oath required. For personal study only.

πŸ“œ SIMILAR VOLUMES

Enzymes in Organic Synthesis, 11. Enanti
Enzymes in Organic Synthesis, 11. Enantioselective Lactonization of Methyl 3,5-Dihydroxyalkanoates. β€” An Access to (3R,5S,6E)-3-Hydroxy-7-phenyl-6-hepten-5-olide by Enzyme-Catalyzed Kinetic Resolution in Organic Solvents
✍ Henkel, Birgitta ;Kunath, Annamarie ;Schick, Hans πŸ“‚ Article πŸ“… 1992 πŸ› John Wiley and Sons 🌐 English βš– 280 KB

## Abstract By enzyme‐catalyzed intramolecular transesterification methyl (Β±)‐(3__R__\*,5__S__\*,6__E__)‐3,5‐dihydroxy‐7‐phenyl‐6‐heptenoate (__rac__‐4) can be enantioselectively converted into the δ‐lactone 5. An enantiomeric excess of 80% was obtained by Pancreatin in diethyl ether at ambient tem