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Resolution of 1- n -Butyl-3-Methyl-3-Phospholene 1-Oxide With TADDOL Derivatives and Calcium Salts of O , O '-Dibenzoyl-(2 R ,3 R )- or O , O '-di- p -Toluoyl-(2 R ,3 R )-tartaric Acid

✍ Scribed by Bagi, Péter; Fekete, András; Kállay, Mihály; Hessz, Dóra; Kubinyi, Miklós; Holczbauer, Tamás; Czugler, Mátyás; Fogassy, Elemér; Keglevich, György


Book ID
125855537
Publisher
John Wiley and Sons
Year
2014
Tongue
English
Weight
812 KB
Volume
26
Category
Article
ISSN
0899-0042

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Racemic N-methylamphetamine can be resolved by O,OЈ-di-ptoluoyltartaric acid in methanol either by the classic Pasteurian method by fractional crystallization of the neutral diastereoisomeric salt pair (molar ratio of the base:acid 2:1) or by the Marckwald or the Pope-Peachey method by fractional cr