Resistance to mitochondrial- and Fas-mediated apoptosis in human leukemic cells with acquired resistance to 9-β-d-arabinofuranosylguanosine
✍ Scribed by Emma Månsson; Helene Stridh; Freidoun Albertioni
- Book ID
- 117052783
- Publisher
- Elsevier Science
- Year
- 2002
- Tongue
- English
- Weight
- 413 KB
- Volume
- 298
- Category
- Article
- ISSN
- 0006-291X
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Apoptosis induced by effector cells of the immune system or by cytotoxic drugs is a main mechanism mediating the prevention or elimination of tumoral cells. For instance, the human T-cell leukemia Jurkat is sensitive to Fas-induced apoptosis and to activation-induced cell death (AICD), and the promo