✦ LIBER ✦

Resistance to challenge and macrophage activity in mice previously vaccinated with formalin-killedCryptococcus neoformans

✍ Scribed by David M. Anderson; Mark A. Dykstra

Book ID: 104774854
Publisher: Springer Netherlands
Year: 1984
Tongue: English
Weight: 614 KB
Volume: 86
Category: Article
ISSN: 0301-486X
DOI: 10.1007/bf00441128

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✦ Synopsis

Mice were vaccinated with formalin-killed Cryptococcus neoformans either intranasally, intravenously, or intraperitoneally. Resistance to lethal challenge and in vitro phagocytic activity of alveolar and peritoneal macrophages was studied. Increased resistance to lethal challenge was seen following vaccination by each of the three routes but increased phagocytic activity was seen only in alveolar macrophages from mice vaccinated intranasally.

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