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Resistance to butyrate-induced cell differentiation and apoptosis during spontaneous Caco-2 cell differentiation

✍ Scribed by John M. Mariadason; Anna Velcich; Andrew J. Wilson; Leonard H. Augenlicht; Peter R. Gibson


Book ID
119756163
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
377 KB
Volume
120
Category
Article
ISSN
0016-5085

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Caco-2 cells differentiate spontaneously when cultured in confluence and on exposure to the physiologically relevant short-chain fatty acid, butyrate. This study aimed to compare the phenotype induced by these pathways and their relations to cell turnover. Caco-2 cells were treated with butyrate at