## Detection of circulating tumor cells in the peripheral blood of patients with androgen-independent, advanced or metastatic prostate cancer To the Editor: The presence of circulating tumor cells (CTC) in the peripheral blood of cancer patients has attracted a great deal of attention among invest
Resistance to Apoptosis and Expansion of Regulatory T Cells in Relation to the Detection of Circulating Tumor Cells in Patients with Metastatic Epithelial Cancer
β Scribed by Stefanie Stanzer; Nadia Dandachi; Marija Balic; Margit Resel; Hellmut Samonigg; Thomas Bauernhofer
- Publisher
- Springer
- Year
- 2007
- Tongue
- English
- Weight
- 281 KB
- Volume
- 28
- Category
- Article
- ISSN
- 0271-9142
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Reduction in apoptosis has been associated with tumor metastases and response to chemotherapy in breast cancer. We examine the influence of apoptosis status and the expression of antiapoptotic proteins Bcl-2 and Bcl-x(L) on metastatic progression and response to therapy in an experimental model of b
## Abstract ## BACKGROUND. The aim of the current study was to assess the prognostic value of baseline circulating tumor cells (CTCs) in a large cohort of patients with newly diagnosed metastatic breast cancer (MBC). ## METHODS. This retrospective study included 185 patients with newly diagnosed