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Resistance of Plasmodium falciparum field isolates to in-vitro artemether and point mutations of the SERCA-type PfATPase6

✍ Scribed by Ronan Jambou; Eric Legrand; Makhtar Niang; Nimol Khim; Pharath Lim; Béatrice Volney; Marie Thérèse Ekala; Christiane Bouchier; Philippe Esterre; Thierry Fandeur; Odile Mercereau-Puijalon


Book ID
117290618
Publisher
The Lancet
Year
2005
Tongue
English
Weight
127 KB
Volume
366
Category
Article
ISSN
0140-6736

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Prevalence of pfcrt point mutations and
✍ Carlo Severini; Michela Menegon; Anna Rosa Sannella; Maria Grazia Paglia; Pasqua 📂 Article 📅 2006 🏛 Elsevier Science 🌐 English ⚖ 133 KB

The development in Plasmodium falciparum of the resistance to chloroquine (CQ) constitutes a public health priority, due to its direct influence in childhood mortality. The molecular basis for CQ resistance (CQR) is still unclear but, recently, a new relevant gene, named pfcrt, with several point mu