## Abstract Discovery of the B cell lymphoma gene 2 (__Bclβ2__ gene) led to the concept that development of cancers required the simultaneous acquisition, not only of deregulated cell division, but also of resistance to programmed cell death or apoptosis. Apoptosis is arguably the common pathway to
Resistance of mtDNA-depleted cells to apoptosis
β Scribed by Roberta Ferraresi; Leonarda Troiano; Marcello Pinti; Erika Roat; Enrico Lugli; Daniela Quaglino; Daniela Taverna; Dina Bellizzi; Giuseppe Passarino; Andrea Cossarizza
- Publisher
- John Wiley and Sons
- Year
- 2008
- Tongue
- English
- Weight
- 691 KB
- Volume
- 73A
- Category
- Article
- ISSN
- 0196-4763
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract Apoptosis is a form of cell death that is manifested in Parkinsonβs disease (PD) and certain other neurodegenerative disorders. Metabolites of salsolinol (SAL), an intraneuronal, dopamineβderived tetrahydroisoquinoline (TIQ), have been shown to induce apoptosis in human dopaminergic neu
The main goal of our study has been to analyze the efficiency of new anticancer drugs, specifically histone deacetylase inhibitors, in tumor cells bearing a multidrug resistance phenotype. We report that the histone deacetylase inhibitors, Trichostatin A and Suberoylanilide Hydroxamic Acid (SAHA), d
Cell senescence and programmed cell death (apoptosis) are two fundamental biological mechanisms that regulate proliferative capacity, survival potential, aging, and death of cells. Here we report several independent lines of experimental evidence that support the hypothesis that telomerase function