Resistance of helper T lymphocytes to cyclophosphamide
β Scribed by Abdul Ghaffar; M.Michael Siegel; Edgar M. Huggins Jr.
- Book ID
- 107927486
- Publisher
- Elsevier Science
- Year
- 1985
- Tongue
- English
- Weight
- 451 KB
- Volume
- 7
- Category
- Article
- ISSN
- 0192-0561
No coin nor oath required. For personal study only.
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Cytotoxic T lymphocytes are major effector cells in responses to viral infections and in allograft rejection and are implicated in many other immunological reactions. Efficient induction of cytotoxic activity in these cells in many but not all cases depends upon helper Tand antigen-presenting cells
## Abstract ## Objective Interleukinβ17 (ILβ17)βproducing T helper cells have been proposed to represent a separate lineage of CD4+ cells, designated Th17 cells, which are regulated by the transcription factor retinoic acidβrelated orphan receptor Ξ³t (RORΞ³t). However, despite advances in understan