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Residue 826 in the Calcium-Sensing Receptor Is Implicated in the Response to Calcium and to R-568 Calcimimetic Compound

✍ Scribed by Daniel Álvarez-Hernández; Ignacio González-Suárez; José L. Fernández-Martín; Isabel Rodríguez; Íñigo Santamaría; Eliecer Coto; Jorge B. Cannata-Andía

Publisher
Springer
Year
2010
Tongue
English
Weight
293 KB
Volume
86
Category
Article
ISSN
1432-0827

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## Abstract Ca^2+^ and the cell‐surface calcium sensing receptor (CaSR) constitute a novel and robust ligand/receptor system in regulating the proliferation and differentiation of colonic epithelial cells. Here we show that activation of CaSR by extracellular Ca^2+^ (or CaSR agonists) enhanced the