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Residue 67 in the DR β1*0101 and DR β1*0103 chains strongly influences antigen presentation and DR-peptide molecular complex conformation

✍ Scribed by F.-E. L'Faqihi; C. Praud; B. Yassine-Diab; G. Enault; F. Lakhdar-Ghazal; C. de Préval; H. Coppin


Book ID
110890799
Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
968 KB
Volume
51
Category
Article
ISSN
0001-2815

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## Abstract Previously, we have proposed that the β1 residues 9–13, 26, 28 and 86 in HLA‐DR17, the most common subtype of DR3, might be critical for the binding of an immunodominant, mycobacterial epitope (peptide 3–13 of the 65‐kDa heat shock protein). In order to examine directly (i) which DR17 r