Resemblance of actin-binding protein/actin gels to covalently crosslinked networks
✍ Scribed by Janmey, Paul A.; Hvidt, Søren; Lamb, Jennifer; Stossel, Thomas P.
- Book ID
- 109763452
- Publisher
- Nature Publishing Group
- Year
- 1990
- Tongue
- English
- Weight
- 451 KB
- Volume
- 345
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/345089a0
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
In muscle cells actin exists as a mixture of monomeric (G-actin) and filamentous actin (F-actin) and ionic conditions strongly favor the formation of F-actin. The existence of unpolymerized actin depends, among other factors, on proteins that bind to G-actin, the so-called G-actin-binding proteins (
Villin, a calcium-regu-dted actin-binding protein, modulates the structure and assembly of actin filaments in vitro. It is organized into three domains, the first two of which are homologous. Villin is mainly produced in epithelial cells that develop a brush border and which are responsible for nutr