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Researchers develop ‘green’ route to indoles


Publisher
Elsevier Science
Year
2004
Weight
34 KB
Volume
2004
Category
Article
ISSN
1351-4180

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✦ Synopsis


Showa Denko has developed a novel solid acid catalyst that allows the production of the pharmaceutical and agrochemical intermediate, alphatetralone, in one step without the generation of waste. Alpha-tetralone is used in the production of the antidepressant sertraline, which achieves sales of Yen 300 bn/y. The market for alpha-tetralone is put at Yen 5 bn and production total 1000 tonne/y, although this is with the production of 6000 tonnes of waste metal compounds.


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