Researchers develop ‘green’ route to indoles
- Publisher
- Elsevier Science
- Year
- 2004
- Weight
- 34 KB
- Volume
- 2004
- Category
- Article
- ISSN
- 1351-4180
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✦ Synopsis
Showa Denko has developed a novel solid acid catalyst that allows the production of the pharmaceutical and agrochemical intermediate, alphatetralone, in one step without the generation of waste. Alpha-tetralone is used in the production of the antidepressant sertraline, which achieves sales of Yen 300 bn/y. The market for alpha-tetralone is put at Yen 5 bn and production total 1000 tonne/y, although this is with the production of 6000 tonnes of waste metal compounds.
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