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✦   LIBER   ✦

Research Progress of Magnetic Resonance Imaging Contrast Agents

✍ Scribed by Yan XIAO; Yi-Jie WU; Wen-Jun ZHANG; Xiao-Jing LI; Feng-Kui PEI

Publisher
Elsevier Science
Year
2011
Tongue
Chinese
Weight
246 KB
Volume
39
Category
Article
ISSN
1872-2040

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✦ Synopsis

Magnetic resonance imaging (MRI ) is one of the most useful diagnostic techniques in clinical medicine and more than 30% of all MRI examinations are accompanied by administration of a contrast agent which has become a class of pharmaceuticals.

The principles, characterization and classification and recent developments of MRI contrast agents are presented in this review. The primary focus of such research is to study the MRI contrast agents with organ-selectivity, high relaxivity and safety.

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## Abstract Magnetic resonance imaging (MRI) produces high‐resolution three‐dimensional maps delineating morphological features of the specimen. Differential contrast in soft tissues depends on endogenous differences in water content, relaxation times, and/or diffusion characteristics of the tissue