Research in the imidazole series. 95. synthesis of derivatives of imidazo[1,5-a]imidazole
β Scribed by P. M. Kochergin; V. A. Lifanov
- Publisher
- Springer US
- Year
- 1994
- Tongue
- English
- Weight
- 428 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0009-3122
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π SIMILAR VOLUMES
## Abstract The Ugi fourβcomponent condensation between 1,1βdiethoxyβ2βisocyanoethane (2), cycloketones 1, amine hydrochlorides 4, and potassium thiocyanate (3a) or selenocyanate (3b) affords spiroimidazoles 5, which are cyclized to spiroimidazo[1,5β__a__]imidazoleβ5βthiones (or selenones) 6.
The solid phase synthesis of [3,5,7]-1H-imidazo[1,5-a]imidazol-2(3H)-ones from acylated dipeptides via cyclization using Bischler-Napieralski conditions is described.
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