Critical intersectional scholarship enhances researchersβ and scholar-activistsβ ability to open novel research frontiers. This forward-thinking Research Handbook demonstrates how to pursue fluid and innovative research approaches, identify differences from traditional methodologies, and overcome the common challenges faced when carrying out intersectional research. A transdisciplinary group of contributors offer their experience and expertise to provide an overview of key research topics, qualitative and quantitative approaches, and empirical examples of integrating intersectionality research with other critical practices. Examining the foundational texts that explain historical developments in systems of oppression and interdisciplinary research on marginalized communities, state-of the-art chapters explore the intersections emerging in studies of gender and sexuality, capitalism, white supremacy, nationalism, colonialism, climate emergencies, imperial decline, and public health. Reconsidering the ways in which scholar-activists carry out research, the Research Handbook demonstrates how an intersectional gaze and a continued commitment to social justice moves us closer to producing valuable research and, ultimately, transforming knowledge. Advancing innovative and multidisciplinary approaches, this incisive Research Handbook will be an invaluable tool for scholars and researchers hoping to undertake meaningful intersectional research. Its empirical findings will further benefit practitioners tasked with designing intersectional policy.