This text provides a broad survey of the role of insulin in the brain. And it discusses the mechanisms through which insulin dysregulation contributes to the development of cognitive impairment and late-life neurodegenerative disease.
[Research and Perspectives in Alzheimer's Disease] Diabetes, Insulin and Alzheimer's Disease || PKC and Insulin Pathways in Memory Storage: Targets for Synaptogenesis, Anti-apoptosis, and the Treatment of AD
β Scribed by Craft, Suzanne; Christen, Yves
- Book ID
- 121494136
- Publisher
- Springer Berlin Heidelberg
- Year
- 2010
- Tongue
- German
- Weight
- 413 KB
- Edition
- 2010
- Category
- Article
- ISBN
- 3642043003
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β¦ Synopsis
This text provides a broad survey of the role of insulin in the brain. And it discusses the mechanisms through which insulin dysregulation contributes to the development of cognitive impairment and late-life neurodegenerative disease.
π SIMILAR VOLUMES
This text provides a broad survey of the role of insulin in the brain. And it discusses the mechanisms through which insulin dysregulation contributes to the development of cognitive impairment and late-life neurodegenerative disease.
This text provides a broad survey of the role of insulin in the brain. And it discusses the mechanisms through which insulin dysregulation contributes to the development of cognitive impairment and late-life neurodegenerative disease.
## Abstract We have evaluated the effect of peripheral insulin deficiency on brain insulin pathway activity in a mouse model of type 1 diabetes, the parallels with Alzheimer's disease (AD), and the effect of treatment with insulin. Nine weeks of insulinβdeficient diabetes significantly impaired the