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Rescuing CD4+CD25+ regulatory T-cell functions in rheumatoid arthritis by cytokine-targeted monoclonal antibody therapy

✍ Scribed by Jagadeesh Bayry; Sophie Sibéril; Frédéric Triebel; David F. Tough; Srini V. Kaveri

Book ID
113568750
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
130 KB
Volume
12
Category
Article
ISSN
1359-6446

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## Abstract ## Objective We previously demonstrated that CD4+,CD25+ regulatory T (Treg) cells are present in increased numbers in the synovial fluid (SF) of rheumatoid arthritis (RA) patients and display enhanced suppressive activity as compared with their peripheral blood (PB) counterparts. Despi