Resampling Procedures for Making Inference Under Nested Case–Control Studies

Resampling-based multiple hypothesis tes

Resampling-based multiple hypothesis testing procedures for genetic case-control association studies

✍ Bingshu E. Chen; Lori C. Sakoda; Ann W. Hsing; Philip S. Rosenberg 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 265 KB 👁 1 views

## Abstract In case‐control studies of unrelated subjects, gene‐based hypothesis tests consider whether any tested feature in a candidate gene—single nucleotide polymorphisms (SNPs), haplotypes, or both—are associated with disease. Standard statistical tests are available that control the false‐pos