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Requirement of vitamin C for cartilage calcification in a differentiating chick limb-bud mesenchymal cell culture

โœ Scribed by Boskey, A.L.; Stiner, D.; Doty, S.B.; Binderman, I.


Book ID
123306384
Publisher
Elsevier Science
Year
1991
Tongue
English
Weight
760 KB
Volume
12
Category
Article
ISSN
8756-3282

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In the presence of 4 mM inorganic phosphate, differentiating chick limb-bud mesenchymal cells plated in micromass cultures form a mineralized matrix resembling that of chick calcified cartilage. To test the hypothesis that cartilage proteoglycans are inhibitors of cell mediated mineralization, the s