The OGG1 gene of Saccharomyces cerevisiae encodes a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine (8-OxoG). When compared to wild-type, ogg1 mutants show an increase in the frequency of GC to TA transversions, indicating a role for Ogg1 in the repair of 8-OxoG. Here we report an increased fr
Requirement of the Saccharomyces cerevisiae APN1 gene for the repair of mitochondrial DNA alkylation damage
β Scribed by Karina Acevedo-Torres; Sharon Fonseca-Williams; Sylvette Ayala-Torres; Carlos A. Torres-Ramos
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 291 KB
- Volume
- 50
- Category
- Article
- ISSN
- 0893-6692
- DOI
- 10.1002/em.20462
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